In the domain of supramolecular catalyst, non-covalent interactions are designed between the partners of the catalytic reaction in order to build catalysts with new functions or modify the catalytic performance of an existing catalyst.[4-5] We propose a new approach in which hydrogen-bonded supramolecular polymers, formed by means of non-covalent interactions between structurally-simple monomers, are used as a scaffold for catalysis. As a proof-of-concept, we performed asymmetric reactions by means of intrinsically achiral metal complexes positioned at the periphery of chiral assemblies. These chiral assemblies are formed either by means of 1,3,5-benzene tricarboxamide (BTA) chiral monomers[1] or mixture of chiral and achiral BTA monomers.[2],[3] 


Selected publications:

[1]: “Tunable asymmetric catalysis through ligand stacking in chiral rigid rods.”
Matthieu. Raynal*, François Portier, Piet W. N. M. van Leeuwen and Laurent Bouteiller,
J. Am. Chem. Soc., 2013, 135, 17687-17690.

[2]: Correlation between the selectivity and the structure of an asymmetric catalyst built on a chirally amplified supramolecular helical scaffold.
Alaric Desmarchelier, Xavier Caumes, Matthieu Raynal,* Anton Vidal-Ferran, Piet W. N. M. van Leeuwen, and Laurent Bouteiller
J. Am. Chem. Soc.,
2016, 138, 4908-4916.                                                                                                           Highlight in Nature Nanotechnology:

[3]: “Real-time control of the enantioselectivity of a supramolecular catalyst allows selecting the configuration of consecutively formed stereogenic centres.
Jeremy M. Zimbron, Xavier Caumes, Yan Li, Christophe M. Thomas, Matthieu Raynal,* and Laurent Bouteiller
Angew. Chem. Int. Ed.,
2017, 56, 14016-14019.                                                  http://onlinelibrary.wiley.comdoi10.1002anie.201706757/            Highlight in Chemistry World:

[4]: “Supramolecular catalysis. Part 1: non-covalent interactions as a tool for building and modifying homogeneous catalysts.”
Matthieu. Raynal*, Pablo Ballester, Anton Vidal-Ferran and Piet W. N. M. van Leeuwen,
Chem. Soc. Rev., 2014, 43, 1660-1733.

[5]: “Supramolecular catalysis. Part 2: artificial enzyme mimics.”
Matthieu. Raynal*, Pablo Ballester, Anton Vidal-Ferran and Piet W. N. M. van Leeuwen,
Chem. Soc. Rev., 2014, 43, 1734-1787.

UMR 8232 : Institut Parisien de Chimie Moléculaire (IPCM)
Chimie des Polymères
Université Paris 6 – CNRS
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